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2 years or older (40 kg or less): 20 mg/kg orally 4 times a day for 5 days. Examples of mild side effects reported with acyclovir include: Diarrhea Difficulty sleeping Dizziness Fatigue (lacking in energy) or feeling tired Fever Flushing or skin redness or unusually warm skin Headache Itching Loss of appetite Menstrual abnormalities Mild skin pain. Immunocompromised host: Less than 1 year: 10 mg/kg IV 3 times a day for 7 to 10 days Adult: 800 mg 5 times daily at approx 4-hourly intervals, omit night time dose. 2 years or older (over 40 kg): 800 mg orally 4 times a day for 5 days. Acyclovir side effects Acyclovir oral tablet doesn’t cause drowsiness but it can cause other side effects. Maximum doses: Single: 800 mg; Daily: 3200 mg/day. 3 The following side effects of acyclovir are rare: abdominal pain dizziness and fatigue hair loss allergic reactions anemia anorexia mood changes, such as aggression or agitation confusion. Make sure you are not affected before you drive or operate machinery. Look on the label and ask the doctor or pharmacist if you are not sure. Acyclovir may cause mild side effects. Alternative dose: 40 kg Same as adult dose. More common side effects Some of the more common side effects of acyclovir oral tablet. Treatment of cold sores and genital herpes The usual dose is one 200 mg tablet taken five times a day You should space your dose by at least four hours Suggested times are: 7am, 11am, 3pm, 7pm and 11pm. Child: 20 mg/kg/dose 4 times daily. Children >40 kg Same as adult dose. 400mg, 800mg TABLETS Take this medicine as your doctor or pharmacist has told you. You should take Aciclovir 800 mg Tablets for seven days.