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Seroquel is used to treat schizophrenia in adults and children who are at least 13 years old. Psychosis can involve what are called positive and negative symptoms.. Many insurance companies require a prior authorization for this drug. Psychosis can involve what are called positive and negative symptoms Seroquel is thought to work by modifying levels of chemicals like dopamine, serotonin, and histamine. Food and Drug Administration (FDA) approved in 1997. Symptoms of schizophrenia include: Hallucinations — imagined voices or images that seem real. Can it make it harder for me to get pregnant? Seroquel is a brand (trade) name for quetiapine which may be used to calm and help diminish psychotic thoughts. An abrupt withdrawal from taking this medication can disrupt this balance.. This is so your progress can be checked. 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